“A novel role for the DYRK1A protein kinase as a chromatin-associated transcriptional regulator”. Chiara Di Vona

Kinases are known to regulate gene expression influencing transcription factors and co-regulators; however, recently it is emerging a new role of these enzymes also in the dynamic of the chromatin structure, since they could modify histones and chromatin remodeling proteins. Little is known on the nuclear function of DYRK1A, an important kinase associated with Down Syndrome. In this short talk, Chiara di Vona suggests a new role of DYRK1A in the regulation of chromatin-associated transcriptional regulators.