The modern microscopy techniques like STORM (stochastic optical reconstruction microscopy) allow us to photograph the structure of the genome within the nucleus. In this work, Maria Aurelia Ricci…
Kinases are known to regulate gene expression influencing transcription factors and co-regulators; however, recently it is emerging a new role of these enzymes also in the dynamic of…
If we compare the size of the complexes that architectural proteins form on the genome, we could define high occupied regions that are enriched at borders of topologically…
The X-chromosome is a fundamental model to study how identical DNA sequences are treated differently from the chromatin organization factors. Exploring the structure of the X-chromosome it is…
Despite the post-translational modification of proteins are mainly considered uncontrolled phenomenon, active enzymes regulate phosphorylation, methylation and oxidation of proteins. Important oxidation processes seem to be crucial for…
The comparison of chromatin features across different human cell types using quantitative model approaches reveals the most important common features regulating the chromatin organization. Moreover, the particular enrichment…
How do cells regulate gene transcription upon a stress? At the Cornell University, Jhon Lis is trying to answer to this question. Using the heat shock response model…
Thomas Cremer was one of the first supporter of the idea that high order chromatin arrangement and architecture of the nucleus are essential for fundamental nuclear functions. T.Cremer…
Each autumn, the Centre for Genomic Regulation leads one of the most exciting scientific events in Barcelona: the CRG Symposium. This year’s 13th edition will be held on…
CRG Symposium 2014