“Lox2 oxidizes methylated TAF10 and controls neural progenitos specification”. Sandra Peiró

Despite the post-translational modification of proteins are mainly considered uncontrolled phenomenon, active enzymes regulate phosphorylation, methylation and oxidation of proteins. Important oxidation processes seem to be crucial for the control of the activity of the “pluripotency-controlling” network, regulated from the well known Yamanaka factors. Novel protein modifications are arising and more studies are needed to understand their functional role.