CRG Symposium 2014BIO Judith Campisi
Buck Institute for Research on Aging, Novato US Judith Campisi has received international recognition for her contributions to understanding why age is the largest single risk factor for developing a panoply of diseases, ranging from neurodegeneration to cancer. Her highly acclaimed research integrates the genetic, environmental and evolutionary forces that result in aging and age-related diseases, and identifies pathways that can be modified to mitigate basic aging processes. Campisi’s laboratory, now at the Buck Institute for Research on Aging, has studied the molecular and cellular links between cancer and aging for more than two decades. They focus on the tumor suppressive senescence response and its relationships to DNA damage signaling, telomere function, proliferation signals, nuclear/chromatin organization and, recently, chronic inflammation. They use simple and complex cell culture and mouse models to understand how senescent cells influence tissue structure and function, aging phenotypes and age-related disease.
Judith Campisi