“Nucleosome from discrete clutches along the chromatin fiber and clutch size correlates with cell pluripotency”. Maria Aurelia Ricci

Thursday, November 6, 2014

The modern microscopy techniques like STORM (stochastic optical reconstruction microscopy) allow us to photograph the structure of the genome within the nucleus. In this work, Maria Aurelia Ricci…

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“The role of architectural proteins in the three-dimensional organization of the chromatin”. Victor Corces

Thursday, November 6, 2014

If we compare the size of the complexes that architectural proteins form on the genome, we could define high occupied regions that are enriched at borders of topologically…

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“Genetic and epigenetic control of x-chromosome inactivation”. Edith Heard

Thursday, November 6, 2014

The X-chromosome is a fundamental model to study how identical DNA sequences are treated differently from the chromatin organization factors. Exploring the structure of the X-chromosome it is…

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“Integrative modeling reveals the principles of multi-scale domain boundary formation in nuclear organization”. Colin A. Semple

Thursday, November 6, 2014

The comparison of chromatin features across different human cell types using quantitative model approaches reveals the most important common features regulating the chromatin organization. Moreover, the particular enrichment…

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“Massive and strikingly similar changes of the nuclear landscape during preimplantation development of fertilized and cloned bovine embryos”. Thomas Cremer

Thursday, November 6, 2014

Thomas Cremer was one of the first supporter of the idea that high order chromatin arrangement and architecture of the nucleus are essential for fundamental nuclear functions. T.Cremer…

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