“Long-range regulation during development and evolution”. Denis Duboule

Friday, November 7, 2014

The formation of digits during development is a high regulated process coordinates by the Hoxd genes. By analyzing the chromosome conformation and Hox transcriptional regulation during the process,…

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“The mRNA binding protein AUF1 controls skeletal muscle stem cell fate, linking AUF1 mutation to the development of limb girdle muscular dystrophy”. Robert J. Schneider

Thursday, November 6, 2014

AU-rich elements (AREs) are known to regulate the mRNA stability and about the 16% of human mRNAs contain this element. The sequence is recognized by specific ARE binding…

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“Targeted and genome-wide views into the mechanisms of transcription and it’s regulation in living cells”. John T.Lis

Thursday, November 6, 2014

How do cells regulate gene transcription upon a stress? At the Cornell University, Jhon Lis is trying to answer to this question. Using the heat shock response model…

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“Massive and strikingly similar changes of the nuclear landscape during preimplantation development of fertilized and cloned bovine embryos”. Thomas Cremer

Thursday, November 6, 2014

Thomas Cremer was one of the first supporter of the idea that high order chromatin arrangement and architecture of the nucleus are essential for fundamental nuclear functions. T.Cremer…

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